GPR45 Back

G protein-coupled receptor 45

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NCBI Description of GPR45

This intronless gene encodes a member of the G protein-coupled receptor (GPCR) family. Members of this protein family contain seven putative transmembrane domains and may mediate signaling processes to the interior of the cell via activation of heterotrimeric G proteins. This protein may function in the central nervous system.

Community Annotation of GPR45 Add / Edit GPR45: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

GPR45 is highly significantly mutated in
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GPR45 is significantly mutated in
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GPR45 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for GPR45