GPR37 Back

G protein-coupled receptor 37 (endothelin receptor type B-like)

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NCBI Description of GPR37

This gene is a member of the G protein-coupled receptor family. The encoded protein contains seven transmembrane domains and is found in cell and endoplasmic reticulum membranes. G protein-coupled receptors are involved in translating outside signals into G protein mediated intracellular effects. This gene product interacts with Parkin and is involved in juvenile Parkinson disease.

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


GPR37 is highly significantly mutated in
GPR37 is significantly mutated in
GPR37 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for GPR37