GPR34 Back

G protein-coupled receptor 34

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NCBI Description of GPR34

G protein-coupled receptors (GPCRs), such as GPR34, are integral membrane proteins containing 7 putative transmembrane domains (TMs). These proteins mediate signals to the interior of the cell via activation of heterotrimeric G proteins that in turn activate various effector proteins, ultimately resulting in a physiologic response.[supplied by OMIM, Apr 2006].

Community Annotation of GPR34 Add / Edit GPR34: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

GPR34 is highly significantly mutated in
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GPR34 is significantly mutated in
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GPR34 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for GPR34