GPR21 Back

G protein-coupled receptor 21

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NCBI Description of GPR21

This gene encodes a member of the G-protein-coupled receptor 1 family. G-protein coupled receptors are membrane proteins which activate signaling cascades as a response to extracellular stress. The encoded protein activates a Gq signal transduction pathway which mobilizes calcium.

Community Annotation of GPR21 Add / Edit GPR21: Annotations

No community annotations yet for GPR21.
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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


GPR21 is highly significantly mutated in
GPR21 is significantly mutated in
GPR21 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for GPR21