GPR119 Back

G protein-coupled receptor 119

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NCBI Description of GPR119
This gene encodes a member of the rhodopsin subfamily of G-protein-coupled receptors that is expressed in the pancreas and gastrointestinal tract. The encoded protein is activated by lipid amides including lysophosphatidylcholine and oleoylethanolamide and may be involved in glucose homeostasis. This protein is a potential drug target in the treatment of type 2 diabetes.

Community Annotation of GPR119 Add / Edit GPR119: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

GPR119 is highly significantly mutated in
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GPR119 is significantly mutated in
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GPR119 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for GPR119