GPC4 Back

glypican 4

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of GPC4
Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The GPC4 gene is adjacent to the 3' end of GPC3 and may also play a role in Simpson-Golabi-Behmel syndrome.

Community Annotation of GPC4 Add / Edit GPC4: Annotations

No community annotations yet for GPC4.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

GPC4 is highly significantly mutated in
(none)
GPC4 is significantly mutated in
(none)
GPC4 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for GPC4