GPC1 Back

glypican 1

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NCBI Description of GPC1

Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation.

Community Annotation of GPC1 Add / Edit GPC1: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


GPC1 is highly significantly mutated in
GPC1 is significantly mutated in
GPC1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for GPC1