GPAM Back

glycerol-3-phosphate acyltransferase, mitochondrial

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NCBI Description of GPAM

This gene encodes a mitochondrial enzyme which prefers saturated fatty acids as its substrate for the synthesis of glycerolipids. This metabolic pathway's first step is catalyzed by the encoded enzyme. Two forms for this enzyme exist, one in the mitochondria and one in the endoplasmic reticulum. Two alternatively spliced transcript variants have been described for this gene.

Community Annotation of GPAM Add / Edit GPAM: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

GPAM is highly significantly mutated in
(none)
GPAM is significantly mutated in
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GPAM is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for GPAM