GNMT Back

glycine N-methyltransferase

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NCBI Description of GNMT
The protein encoded by this gene is an enzyme that catalyzes the conversion of S-adenosyl-L-methionine (along with glycine) to S-adenosyl-L-homocysteine and sarcosine. The encoded protein is found in the cytoplasm and acts as a homotetramer. Defects in this gene are a cause of GNMT deficiency (hypermethioninemia).

Community Annotation of GNMT Add / Edit GNMT: Annotations

No community annotations yet for GNMT.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

GNMT is highly significantly mutated in
(none)
GNMT is significantly mutated in
(none)
GNMT is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for GNMT