GNL3 Back

guanine nucleotide binding protein-like 3 (nucleolar)

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NCBI Description of GNL3

The protein encoded by this gene may interact with p53 and may be involved in tumorigenesis. The encoded protein also appears to be important for stem cell proliferation. This protein is found in both the nucleus and nucleolus. Three transcript variants encoding two different isoforms have been found for this gene.

Community Annotation of GNL3 Add / Edit GNL3: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


GNL3 is highly significantly mutated in
GNL3 is significantly mutated in
GNL3 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for GNL3