GNG3 Back

guanine nucleotide binding protein (G protein), gamma 3

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NCBI Description of GNG3

Guanine nucleotide binding proteins are heterotrimeric signal-transducing molecules consisting of alpha, beta, and gamma subunits. The gamma subunit determines the specificity of which signaling pathways will be affected by this particular complex. The protein encoded by this gene represents the gamma subunit of both inhibitory and stimulatory complexes.

Community Annotation of GNG3 Add / Edit GNG3: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


GNG3 is highly significantly mutated in
GNG3 is significantly mutated in
GNG3 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for GNG3