GNG13 Back

guanine nucleotide binding protein (G protein), gamma 13

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NCBI Description of GNG13

Heterotrimeric G proteins, which consist of alpha (see MIM 139320), beta (see MIM 139380), and gamma subunits, function as signal transducers for the 7-transmembrane-helix G protein-coupled receptors. GNG13 is a gamma subunit that is expressed in taste, retinal, and neuronal tissues and plays a key role in taste transduction (Li et al., 2006 [PubMed 16473877]).[supplied by OMIM, Oct 2009].

Community Annotation of GNG13 Add / Edit GNG13: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

GNG13 is highly significantly mutated in
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GNG13 is significantly mutated in
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GNG13 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for GNG13