GNB5 Back

guanine nucleotide binding protein (G protein), beta 5

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NCBI Description of GNB5

Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. Alternatively spliced transcript variants encoding different isoforms exist.

Community Annotation of GNB5 Add / Edit GNB5: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

GNB5 is highly significantly mutated in
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GNB5 is significantly mutated in
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GNB5 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for GNB5