GNB4 Back

guanine nucleotide binding protein (G protein), beta polypeptide 4

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NCBI Description of GNB4
Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors.

Community Annotation of GNB4 Add / Edit GNB4: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

GNB4 is highly significantly mutated in
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GNB4 is significantly mutated in
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GNB4 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for GNB4