GNA14 Back

guanine nucleotide binding protein (G protein), alpha 14

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NCBI Description of GNA14

This gene encodes a member of the guanine nucleotide-binding, or G protein family. G proteins are heterotrimers consisting of alpha, beta and gamma subunits. The encoded protein is a member of the alpha family of G proteins, more specifically the alpha q subfamily of G proteins. The encoded protein may play a role in pertussis-toxin resistant activation of phospholipase C-beta and its downstream effectors.

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


GNA14 is highly significantly mutated in
GNA14 is significantly mutated in
GNA14 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for GNA14