GDP-mannose pyrophosphorylase B

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NCBI Description of GMPPB

This gene is thought to encode a GDP-mannose pyrophosphorylase. The encoded protein catalyzes the conversion of mannose-1-phosphate and GTP to GDP-mannose, a reaction involved in the production of N-linked oligosaccharides. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Community Annotation of GMPPB Add / Edit GMPPB: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


GMPPB is highly significantly mutated in
GMPPB is significantly mutated in
GMPPB is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for GMPPB