GMIP Back

GEM interacting protein

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NCBI Description of GMIP
This gene encodes a member of the ARHGAP family of Rho/Rac/Cdc42-like GTPase activating proteins. The encoded protein interacts with the Ras-related protein Gem through its N-terminal domain. Separately, it interacts with RhoA through a RhoGAP domain, and stimulates RhoA-dependent GTPase activity. Alternatively spliced variants that encode different protein isoforms have been described but their full-length nature has not been determined.

Community Annotation of GMIP Add / Edit GMIP: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

GMIP is highly significantly mutated in
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GMIP is significantly mutated in
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GMIP is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for GMIP