GMCL1 Back

germ cell-less homolog 1 (Drosophila)

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NCBI Description of GMCL1

This gene encodes a nuclear envelope protein that appears to be involved in spermatogenesis, either directly or by influencing genes that play a more direct role in the process. This multi-exon locus is the homolog of the mouse and drosophila germ cell-less gene but the human genome also contains a single-exon locus on chromosome 5 that contains an open reading frame capable of encoding a highly-related protein.

Community Annotation of GMCL1 Add / Edit GMCL1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

GMCL1 is highly significantly mutated in
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GMCL1 is significantly mutated in
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GMCL1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for GMCL1