GLIPR1 Back

GLI pathogenesis-related 1 (glioma)

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of GLIPR1
This gene encodes a protein with similarity to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family. Increased expression of this gene is associated with myelomocytic differentiation in macrophage and decreased expression of this gene through gene methylation is associated with prostate cancer. The protein has proapoptotic activities in prostate and bladder cancer cells. This gene is a member of a cluster on chromosome 12 containing two other similar genes. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.

Community Annotation of GLIPR1 Add / Edit GLIPR1: Annotations

No community annotations yet for GLIPR1.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

GLIPR1 is highly significantly mutated in
(none)
GLIPR1 is significantly mutated in
(none)
GLIPR1 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for GLIPR1