GJD2 Back

gap junction protein, delta 2, 36kDa

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NCBI Description of GJD2
This gene encodes a member of the connexin protein family. Connexins are gap junction proteins which are arranged in groups of 6 around a central pore to form a connexon, a component of the gap junction intercellular channel. The channels formed by this protein allow cationic molecule exchange between human beta cells and may function in the regulation of insulin secretion.

Community Annotation of GJD2 Add / Edit GJD2: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

GJD2 is highly significantly mutated in
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GJD2 is significantly mutated in
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GJD2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for GJD2