GINS2 Back

GINS complex subunit 2 (Psf2 homolog)

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NCBI Description of GINS2

The yeast heterotetrameric GINS complex is made up of Sld5 (GINS4; MIM 610611), Psf1 (GINS1; MIM 610608), Psf2, and Psf3 (GINS3; MIM 610610). The formation of this complex is essential for the initiation of DNA replication in yeast and Xenopus egg extracts (Ueno et al., 2005 [PubMed 16287864]). See GINS1 for additional information about the GINS complex.[supplied by OMIM, Mar 2008].

Community Annotation of GINS2 Add / Edit GINS2: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

GINS2 is highly significantly mutated in
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GINS2 is significantly mutated in
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GINS2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for GINS2