GGT6 Back

gamma-glutamyltransferase 6

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of GGT6
GGT6 belongs to the gamma-glutamyltransferase (GGT; EC 2.3.2.2) gene family. GGT is a membrane-bound extracellular enzyme that cleaves gamma-glutamyl peptide bonds in glutathione and other peptides and transfers the gamma-glutamyl moiety to acceptors. GGT is also key to glutathione homeostasis because it provides substrates for glutathione synthesis (Heisterkamp et al., 2008 [PubMed 18357469]).[supplied by OMIM, Oct 2008].

Community Annotation of GGT6 Add / Edit GGT6: Annotations

No community annotations yet for GGT6.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

GGT6 is highly significantly mutated in
(none)
GGT6 is significantly mutated in
(none)
GGT6 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for GGT6