GFPT1 Back

glutamine-fructose-6-phosphate transaminase 1

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NCBI Description of GFPT1

This gene encodes the first and rate-limiting enzyme of the hexosamine pathway and controls the flux of glucose into the hexosamine pathway. The product of this gene catalyzes the formation of glucosamine 6-phosphate.

Community Annotation of GFPT1 Add / Edit GFPT1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

GFPT1 is highly significantly mutated in
(none)
GFPT1 is significantly mutated in
(none)
GFPT1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for GFPT1