NCBI Description of GEMIN5
|This gene encodes a WD repeat protein that is a component of the survival of motor neurons (SMN) complex. The SMN complex plays a critical role in mRNA splicing through the assembly of spliceosomal small nuclear ribonucleoproteins (snRNPs), and may also mediate the assembly and transport of other classes of ribonucleoproteins. The encoded protein is the snRNA-binding component of the SMN complex. Dysregulation of this gene may play a role in alternative mRNA splicing and tumor cell motility. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.|
Community Annotation of GEMIN5 Add / Edit GEMIN5: Annotations
No community annotations yet for GEMIN5.
• "Mouse over" a mutation to see details.
Click on a tumor type to see its full list of significant genes.