GEM Back

GTP binding protein overexpressed in skeletal muscle

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NCBI Description of GEM

The protein encoded by this gene belongs to the RAD/GEM family of GTP-binding proteins. It is associated with the inner face of the plasma membrane and could play a role as a regulatory protein in receptor-mediated signal transduction. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.

Community Annotation of GEM Add / Edit GEM: Annotations

No community annotations yet for GEM.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

GEM is highly significantly mutated in
(none)
GEM is significantly mutated in
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GEM is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for GEM