GDF7 Back

growth differentiation factor 7

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NCBI Description of GDF7
This gene encodes a member of the bone morphogenetic protein (BMP) family. BMPs belong to the transforming growth factor-beta superfamily of secreted signalling molecules that regulate diverse processes in growth, repair and embryonic development. In mouse, this gene functions as an inductive signal from the roof plate required for the specification of neuronal identity in the dorsal spinal cord.

Community Annotation of GDF7 Add / Edit GDF7: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

GDF7 is highly significantly mutated in
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GDF7 is significantly mutated in
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GDF7 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for GDF7