GDF3 Back

growth differentiation factor 3

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NCBI Description of GDF3
The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues.

Community Annotation of GDF3 Add / Edit GDF3: Annotations

No community annotations yet for GDF3.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

GDF3 is highly significantly mutated in
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GDF3 is significantly mutated in
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GDF3 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for GDF3