GBGT1 Back

globoside alpha-1,3-N-acetylgalactosaminyltransferase 1

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NCBI Description of GBGT1
This gene encodes a member of the histo-blood group ABO gene family that encodes glycosyltransferases with related but distinct substrate specificity. This protein plays a role in synthesizing Forssman glycolipid (FG), a member of the globoseries glycolipid family. Human cells do not normally produce FG but produce the precursor glycolipids globotriaosylceramide and globoside. This protein may be involved in the tropism and binding of pathogenic organisms. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.

Community Annotation of GBGT1 Add / Edit GBGT1: Annotations

No community annotations yet for GBGT1.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

GBGT1 is highly significantly mutated in
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GBGT1 is significantly mutated in
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GBGT1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for GBGT1