NCBI Description of GBF1
|This gene encodes a member of the Sec7 domain family. The encoded protein is a guanine nucleotide exchange factor that regulates the recruitment of proteins to membranes by mediating GDP to GTP exchange. The encoded protein is localized to the Golgi apparatus and plays a role in vesicular trafficking by activating ADP ribosylation factor 1. The encoded protein has also been identified as an important host factor for viral replication. Multiple transcript variants have been observed for this gene.|
Community Annotation of GBF1 Add / Edit GBF1: Annotations
No community annotations yet for GBF1.
• "Mouse over" a mutation to see details.
Click on a tumor type to see its full list of significant genes.