GBA2 Back

glucosidase, beta (bile acid) 2

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NCBI Description of GBA2
This gene encodes a microsomal beta-glucosidase that catalyzes the hydrolysis of bile acid 3-O-glucosides as endogenous compounds. Studies to determine subcellular localization of this protein in the liver indicated that the enzyme was mainly enriched in the microsomal fraction where it appeared to be confined to the endoplasmic reticulum. This putative transmembrane protein is thought to play a role in carbohydrate transport and metabolism.

Community Annotation of GBA2 Add / Edit GBA2: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

GBA2 is highly significantly mutated in
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GBA2 is significantly mutated in
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GBA2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for GBA2