GATA6 Back

GATA binding protein 6

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NCBI Description of GATA6
This gene is a member of a small family of zinc finger transcription factors that play an important role in the regulation of cellular differentiation and organogenesis during vertebrate development. This gene is expressed during early embryogenesis and localizes to endo- and mesodermally derived cells during later embryogenesis and thereby plays an important role in gut, lung, and heart development. Mutations in this gene are associated with several congenital defects.

Community Annotation of GATA6 Add / Edit GATA6: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

GATA6 is highly significantly mutated in
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GATA6 is significantly mutated in
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GATA6 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for GATA6