GATA4 Back

GATA binding protein 4

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NCBI Description of GATA4

This gene encodes a member of the GATA family of zinc-finger transcription factors. Members of this family recognize the GATA motif which is present in the promoters of many genes. This protein is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function. Mutations in this gene have been associated with cardiac septal defects.

Community Annotation of GATA4 Add / Edit GATA4: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

GATA4 is highly significantly mutated in
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GATA4 is significantly mutated in
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GATA4 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for GATA4