GAP43 Back

growth associated protein 43

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NCBI Description of GAP43

The protein encoded by this gene has been termed a 'growth' or 'plasticity' protein because it is expressed at high levels in neuronal growth cones during development and axonal regeneration. This protein is considered a crucial component of an effective regenerative response in the nervous system. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Community Annotation of GAP43 Add / Edit GAP43: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


GAP43 is highly significantly mutated in
GAP43 is significantly mutated in
GAP43 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for GAP43