GAP43 Back

growth associated protein 43

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NCBI Description of GAP43
The protein encoded by this gene has been termed a 'growth' or 'plasticity' protein because it is expressed at high levels in neuronal growth cones during development and axonal regeneration. This protein is considered a crucial component of an effective regenerative response in the nervous system. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Community Annotation of GAP43 Add / Edit GAP43: Annotations

No community annotations yet for GAP43.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

GAP43 is highly significantly mutated in
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GAP43 is significantly mutated in
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GAP43 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for GAP43