GAGE1 Back

G antigen 1

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NCBI Description of GAGE1
This gene belongs to a family of genes that are expressed in a variety of tumors but not in normal tissues, except for the testis. The sequences of the family members are highly related but differ by scattered nucleotide substitutions. The antigenic peptide YRPRPRRY, which is also encoded by several other family members, is recognized by autologous cytolytic T lymphocytes. Nothing is presently known about the function of this protein. Alternative splicing results in multiple transcript variants.

Community Annotation of GAGE1 Add / Edit GAGE1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

GAGE1 is highly significantly mutated in
(none)
GAGE1 is significantly mutated in
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GAGE1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for GAGE1