gamma-aminobutyric acid (GABA) A receptor, pi

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NCBI Description of GABRP

The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. The subunit encoded by this gene is expressed in several non-neuronal tissues including the uterus and ovaries. This subunit can assemble with known GABA A receptor subunits, and the presence of this subunit alters the sensitivity of recombinant receptors to modulatory agents such as pregnanolone.

Community Annotation of GABRP Add / Edit GABRP: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


GABRP is highly significantly mutated in
GABRP is significantly mutated in
GABRP is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for GABRP