GABRG2 Back

gamma-aminobutyric acid (GABA) A receptor, gamma 2

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of GABRG2
This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures. Multiple transcript variants encoding different isoforms have been identified for this gene.

Community Annotation of GABRG2 Add / Edit GABRG2: Annotations

No community annotations yet for GABRG2.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

GABRG2 is highly significantly mutated in
(none)
GABRG2 is significantly mutated in
(none)
GABRG2 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for GABRG2