GABRA6 Back

gamma-aminobutyric acid (GABA) A receptor, alpha 6

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NCBI Description of GABRA6
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because transcript sequence consistent with the reference genome assembly was not available for all regions of the RefSeq transcript. The extent of this transcript is supported by transcript alignments.

Community Annotation of GABRA6 Add / Edit GABRA6: Annotations

No community annotations yet for GABRA6.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

GABRA6 is highly significantly mutated in
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GABRA6 is significantly mutated in
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GABRA6 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for GABRA6