GABPB1 Back

GA binding protein transcription factor, beta subunit 1

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NCBI Description of GABPB1
This gene encodes the GA-binding protein transcription factor, beta subunit. This protein forms a tetrameric complex with the alpha subunit, and stimulates transcription of target genes. The encoded protein may be involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. The crystal structure of a similar protein in mouse has been resolved as a ternary protein complex. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

GABPB1 is highly significantly mutated in
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GABPB1 is significantly mutated in
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GABPB1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for GABPB1