FZD3 Back

frizzled homolog 3 (Drosophila)

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NCBI Description of FZD3
This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. The function of this protein is unknown, although it may play a role in mammalian hair follicle development. Alternative splicing results in multiple transcript variants. This gene is a susceptibility locus for schizophrenia.

Community Annotation of FZD3 Add / Edit FZD3: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

FZD3 is highly significantly mutated in
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FZD3 is significantly mutated in
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FZD3 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for FZD3