FZD10 Back

frizzled homolog 10 (Drosophila)

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NCBI Description of FZD10

This gene is a member of the frizzled gene family. Members of this family encode 7-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Using array analysis, expression of this intronless gene is significantly up-regulated in two cases of primary colon cancer.

Community Annotation of FZD10 Add / Edit FZD10: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

FZD10 is highly significantly mutated in
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FZD10 is significantly mutated in
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FZD10 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for FZD10