FYN Back

FYN oncogene related to SRC, FGR, YES

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of FYN

This gene is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein. Alternatively spliced transcript variants encoding distinct isoforms exist.

Community Annotation of FYN Add / Edit FYN: Annotations

No community annotations yet for FYN.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


FYN is highly significantly mutated in
FYN is significantly mutated in
FYN is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for FYN