FXR1 Back

fragile X mental retardation, autosomal homolog 1

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NCBI Description of FXR1

The protein encoded by this gene is an RNA binding protein that interacts with the functionally-similar proteins FMR1 and FXR2. These proteins shuttle between the nucleus and cytoplasm and associate with polyribosomes, predominantly with the 60S ribosomal subunit. Three transcript variants encoding different isoforms have been found for this gene.

Community Annotation of FXR1 Add / Edit FXR1: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


FXR1 is highly significantly mutated in
FXR1 is significantly mutated in
FXR1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for FXR1