FUZ Back

fuzzy homolog (Drosophila)

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NCBI Description of FUZ
This gene encodes a planar cell polarity protein that is involved in ciliogenesis and directional cell movement. Knockout studies in mice exhibit neural tube defects and defective cilia, and mutations in this gene are associated with neural tube defects in humans. Alternatively spliced transcript variants have been found for this gene.

Community Annotation of FUZ Add / Edit FUZ: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

FUZ is highly significantly mutated in
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FUZ is significantly mutated in
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FUZ is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for FUZ