FUT9 Back

fucosyltransferase 9 (alpha (1,3) fucosyltransferase)

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of FUT9
The protein encoded by this gene belongs to the glycosyltransferase family. It is localized to the golgi, and catalyzes the last step in the biosynthesis of Lewis X (LeX) antigen, the addition of a fucose to precursor polysaccharides. This protein is one of the few fucosyltransferases that synthesizes the LeX oligosaccharide (CD15) expressed in the organ buds progressing in mesenchyma during embryogenesis. It is also responsible for the expression of CD15 in mature granulocytes. A common haplotype of this gene has also been associated with susceptibility to placental malaria infection. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments.

Community Annotation of FUT9 Add / Edit FUT9: Annotations

No community annotations yet for FUT9.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

FUT9 is highly significantly mutated in
(none)
FUT9 is significantly mutated in
(none)
FUT9 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for FUT9