FUT2 Back

fucosyltransferase 2 (secretor status included)

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NCBI Description of FUT2

The protein encoded by this gene is a Golgi stack membrane protein that is involved in the creation of a precursor of the H antigen, which is required for the final step in the soluble A and B antigen synthesis pathway. This gene is one of two encoding the galactoside 2-L-fucosyltransferase enzyme. Two transcript variants encoding the same protein have been found for this gene.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

FUT2 is highly significantly mutated in
(none)
FUT2 is significantly mutated in
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FUT2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for FUT2