FUCA1 Back

fucosidase, alpha-L- 1, tissue

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NCBI Description of FUCA1
The protein encoded by this gene is a lysosomal enzyme involved in the degradation of fucose-containing glycoproteins and glycolipids. Mutations in this gene are associated with fucosidosis (FUCA1D), which is an autosomal recessive lysosomal storage disease. A pseudogene of this locus is present on chr 2.

Community Annotation of FUCA1 Add / Edit FUCA1: Annotations

No community annotations yet for FUCA1.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

FUCA1 is highly significantly mutated in
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FUCA1 is significantly mutated in
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FUCA1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for FUCA1