FST Back

follistatin

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of FST
Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release. The single FST gene encodes two isoforms, FST317 and FST344 containing 317 and 344 amino acids respectively, resulting from alternative splicing of the precursor mRNA. In a study in which 37 candidate genes were tested for linkage and association with polycystic ovary syndrome (PCOS) or hyperandrogenemia in 150 families, evidence was found for linkage between PCOS and follistatin.

Community Annotation of FST Add / Edit FST: Annotations

No community annotations yet for FST.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

FST is highly significantly mutated in
(none)
FST is significantly mutated in
(none)
FST is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for FST