FSCN2 Back

fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus)

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of FSCN2
This gene encodes a member of the fascin protein family. Fascins crosslink actin into filamentous bundles within dynamic cell extensions. This family member is proposed to play a role in photoreceptor disk morphogenesis. A mutation in this gene results in one form of autosomal dominant retinitis pigmentosa and macular degeneration. Multiple transcript variants encoding different isoforms have been found for this gene.

Community Annotation of FSCN2 Add / Edit FSCN2: Annotations

No community annotations yet for FSCN2.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

FSCN2 is highly significantly mutated in
(none)
FSCN2 is significantly mutated in
(none)
FSCN2 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for FSCN2