FRMPD4 Back

FERM and PDZ domain containing 4

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of FRMPD4
This gene encodes a multi-domain (WW, PDZ, FERM) containing protein. Through its interaction with other proteins (such as PSD-95), it functions as a positive regulator of dendritic spine morphogenesis and density, and is required for the maintenance of excitatory synaptic transmission. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.

Community Annotation of FRMPD4 Add / Edit FRMPD4: Annotations

No community annotations yet for FRMPD4.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

FRMPD4 is highly significantly mutated in
(none)
FRMPD4 is significantly mutated in
(none)
FRMPD4 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for FRMPD4