FOXR1 Back

forkhead box R1

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NCBI Description of FOXR1

This gene encodes a member of the forkhead box (FOX) family of transcription factors. FOX family members are monomeric, helix-turn-helix proteins with a core DNA-binding domain of approximately 110 aa. Many FOX transcription factors play roles in determining cell fates during early development. This forkhead box protein lacks the C-terminal basic region found in many other FOX family members. It is located within the 11q23.3 region which is commonly deleted in neuroblastomas.

Community Annotation of FOXR1 Add / Edit FOXR1: Annotations

No community annotations yet for FOXR1.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

FOXR1 is highly significantly mutated in
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FOXR1 is significantly mutated in
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FOXR1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for FOXR1